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Patient Profiles

Angela
(she/her)
Angela
Actor portrayals.
Age
40
Marital Status
Divorced, mother of 2
Profession
Teacher
Diagnosis
Generalized anxiety disorder (GAD) @ 38 years old
GAD Treatment
Lorazepam 0.5 mg TID
Other Treatments
Cognitive behavioral therapy
Comorbidities
None
Insurance
PPO provided by employer

Angela's challenge:

She is worried about missing a dose during the day yet does not want to carry medication with her into her classroom.

In recent office visits:

With the newfound responsibilities of single parenthood since her divorce, Angela reported being very worried about how her anxiety may affect her.

Angela's doctor prescribed lorazepam 0.5 mg TID. This is helping, but she finds it challenging to take the midday dose. She would like to know if a once-daily lorazepam option is available.

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References:

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  2. Saltel DA, Vachon M. Edgemont Pharmaceuticals LLC. Sustained release formulations of lorazepam. US patent 8,999,393 B1. April 7, 2015.
  3. Altamura AC, Moliterno D, Paletta S, Maffini M, Mauri MC, Bareggi S. Understanding the pharmacokinetics of anxiolytic drugs. Expert Opin Drug Metab Toxicol. 2013;9(4):423-440.
  4. Data on file. Almatica Pharma LLC; 2020.
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  6. Ogu CC, Maxa JL. Drug interactions due to cytochrome P450. Proc (Bayl Univ Med Cent). 2000;13(4):421-423.
  7. Deodhar M, Al Rihani SB, Arwood MJ, et al. Mechanisms of CYP450 inhibition: understanding drug-drug interactions due to mechanism-based inhibition in clinical practice.Pharmaceutics. 2020;12(9):846.
  8. Ramadan MI, Werder SF, Preskorn SH. Protect against drug-drug interactions with anxiolytics.Curr Psychiatry. 2006;5(5):16-28.
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  21. Trintellix. Prescribing information. Takeda Pharmaceuticals America, Inc; 2023.
  22. Venlafaxine. Prescribing information. Almatica Pharma LLC; 2023.